Peptide Research
Research Library
Compound hubs grouped by receptor and structural class, molecular comparisons, laboratory handling material and batch documentation. Each compound is described by what it is and what it binds: its sequence, class, mass and registry number, and how its identity and purity are established by HPLC and mass spectrometry. Everything here is written for in-vitro laboratory research.
Compound Library
Reference pages on molecular identity and structure: what each compound is, the experiments behind what is known about it, and what remains unresolved. 23 of 23 entries are available.
- AOD-9604Peptide
- BPC-157Peptide
- CagrilintidePeptide
- CJC-1295 with DACPeptide
- CJC-1295 without DACPeptide
- DSIPPeptide
Compound research hubs
One page per compound, collecting every vial size, its identity record, the molecular comparisons worth reading, the handling material and any certificate a laboratory has issued.
Research by receptor and structural class
Incretin, glucagon and amylin receptor agonists
Peptide agonists at the class B G protein-coupled receptors for GLP-1, GIP and glucagon, singly or in dual and triple combination, and the amylin analogue cagrilintide. Laboratory work on this class measures receptor potency and selectivity in cAMP accumulation assays, the effect of fatty-acid acylation on albumin binding, and identity by HPLC and mass spectrometry. SLU-PP-332, a small-molecule estrogen-related receptor agonist, and AOD-9604, a modified hGH(177-191) fragment, are filed here as structural comparators.
Peptide fragments, thymic peptides and redox-active peptides
Short sequences derived from larger proteins and the peptides filed beside them: BPC-157, a pentadecapeptide fragment of a gastric protein; TB-500, the Ac-LKKTETQ actin-binding fragment of thymosin beta-4; SS-31, a cardiolipin-binding mitochondria-targeted tetrapeptide; glutathione, the thiol tripeptide; and thymosin alpha-1, a 28-residue acetylated peptide derived from prothymosin alpha. Laboratory work here measures sequence identity, actin and cardiolipin binding, thiol oxidation state, and signalling such as VEGFR2 and eNOS phosphorylation in endothelial cell culture.
Copper peptide complexes
GHK-Cu, the copper(II) complex of the tripeptide Gly-His-Lys, and the related copper-binding sequences it is compared with. Laboratory work on this class measures copper coordination and the stoichiometry of the complex, its stability in solution, and gene-expression and extracellular-matrix protein readouts in fibroblast cell culture.
GHRH analogues, ghrelin-receptor agonists and IGF-1 analogues
Two receptor pharmacologies and one downstream ligand. GHRH analogues (sermorelin, CJC-1295 with and without DAC, tesamorelin) act at the GHRH receptor; ipamorelin acts at the ghrelin receptor GHS-R1a; IGF-1 LR3 is an IGF-1 receptor ligand with reduced IGF-binding-protein affinity. Laboratory work here measures receptor selectivity, the effect of the DAC lysine-maleimide linker on albumin conjugation, and identity by HPLC and mass spectrometry.
Neuropeptide analogues, melanocortin ligands and mitochondrial-derived peptides
Several classes that share a shelf rather than a receptor, each placed by its own structure: MOTS-c, a 16-residue peptide encoded in the mitochondrial 12S rRNA gene; Selank and Semax, synthetic analogues of tuftsin and of ACTH(4-10) extended with Pro-Gly-Pro; PT-141 (bremelanotide), a cyclic MC3R and MC4R agonist, and KPV, the C-terminal Lys-Pro-Val tripeptide of alpha-MSH; DSIP, the nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu; epithalon, the tetrapeptide Ala-Glu-Asp-Gly; and HCG, a glycoprotein hormone and LH/CG receptor agonist. Each compound hub below states its own structure and the model each finding came from.
Browse the full library
The collections below are paginated and crawlable in full. They are a complete index of what has been published, not a recommendation: a page appearing here has not necessarily been through editorial review.
Research pages are being generated. Check back soon.
