Compound research hub
MOTS-c: Research, Handling and Batch Documentation
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA gene, described in 2015, whose reported molecular action is activation of AMPK.
Part of Volta's peptides.
Identity and specification
- Form
- Lyophilized powder
- Appearance
- White lyophilised powder
- Full chemical name
- Mitochondrial open reading frame of the 12S rRNA type-c
- Other known names
- Mitochondrial-Derived Peptide
- Compound class
- Mitochondrial peptide
- Sequence, one-letter
- MRWQEMGYIFYPRKLR
- Sequence, three-letter
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Residues
- 16
- CAS number
- 1627580-64-6
- Molecular formula
- C₁₀₁H₁₅₂N₂₈O₂₂S₂
- Molecular weight
- 2,174.6 g/mol
- PubChem SID
- 255386757
- Production
- Synthetic, by solid-phase peptide synthesis
- Solubility
- Soluble in sterile water
- Shelf life
- 24 months from date of manufacture
Molecular structure, sequence and the published laboratory studies on MOTS-c are in the compound library entry for MOTS-c.
Vial sizes available
Every size of MOTS-c Volta lists, in stock or not. Each is a separate catalogue page with its own batch number and specification table.
- In stock
MOTS-C 10mg 10mgBatch #: VPMC10100 - Restocking
MOTS-C 20mg 20mgBatch #: VPMC20100
Purity and batch documentation
Volta's release specification is >99% (HPLC). That is a threshold we set. >99% is the specification every batch is released to. The figure on a certificate is what a laboratory measured for one lot.
SideChain Analytics reported 99.4% by HPLC-MS/MS on September 27, 2026, lot VPMC10100.
Covers the MOTS-C 10mg vial.
Research on MOTS-c
Handling and stability
Laboratory guides
Regulatory context
More peptides
MOTS-c sits in Volta's peptides group, alongside the other compounds of the same composition. The whole range is on the full research catalogue, and the library of comparisons and guides is under peptide research.