SS-31 10mg Peptide

SS-31 targets cardiolipin, the signature phospholipid of the inner mitochondrial membrane, and its alternating aromatic-cationic motif is what drives that association without requiring a membrane potential to accumulate. Binding cardiolipin stabilises cristae architecture and appears to improve electron transport coupling, which is the mechanistic basis for interest in ischemia-reperfusion, heart failure and mitochondrial myopathy models. The compound has run through several clinical programmes under the name elamipretide, so its pharmacokinetics are better characterised than most research peptides.