ARA-290 10mg Peptide
Research Use Only
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Research Use Only
For in vitro laboratory research by qualified professionals only. Not for human or animal administration. Not intended to treat, prevent, mitigate, or cure any disease. Batch-specific Certificates of Analysis available for all products.
Research Use Only
For in vitro laboratory research by qualified professionals only. Not for human or animal administration. Not intended to treat, prevent, mitigate, or cure any disease. Batch-specific Certificates of Analysis available for all products.
Erythropoietin has a tissue-protective function that is entirely separate from its haematopoietic one, mediated by a heteromeric receptor of EPOR and the beta common receptor rather than by the EPOR homodimer. ARA-290 is engineered to hit only the former. That separation is the whole point of the molecule: it allows the anti-inflammatory and neuroprotective activity of EPO to be studied without the haematocrit rise and thrombotic risk that make the parent hormone unusable for that purpose. It has been investigated in small-fibre neuropathy and sarcoidosis models.
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