Thymosin Alpha-1 10mg Peptide
Research Use Only
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Research Use Only
For in vitro laboratory research by qualified professionals only. Not for human or animal administration. Not intended to treat, prevent, mitigate, or cure any disease. Batch-specific Certificates of Analysis available for all products.
Research Use Only
For in vitro laboratory research by qualified professionals only. Not for human or animal administration. Not intended to treat, prevent, mitigate, or cure any disease. Batch-specific Certificates of Analysis available for all products.
Unlike Thymalin, which is a tissue-derived fraction, Thymosin Alpha-1 is a single defined sequence, which makes it the more tractable of the two for mechanistic work. Its activity appears to run largely through TLR2 and TLR9 on dendritic cells, shifting T-cell differentiation toward a Th1 profile. That mechanism underpins its approved use as an immune adjuvant in hepatitis B and C in a number of countries, and it accumulated a large dataset during COVID-19 research. Its immune activity is context-dependent, restoring depressed responses more than amplifying normal ones.
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