Adamax Adamantane 10mg Peptide
For in-vitro laboratory research only. Not for human or animal administration.
Batch #: VPAA10100
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Research Use Only
For in-vitro laboratory research by qualified professionals only. Not for human or animal administration. Not a drug, food, cosmetic or dietary supplement. Not intended to diagnose, treat, cure, mitigate or prevent any disease. Batch-specific Certificates of Analysis available for all products.
Adamax Adamantane 10mg: overview
What the vial contains and what the material is, stated as specifications rather than as outcomes.
Adamax Adamantane supplied as a lyophilized powder in a sealed single-use vial containing 10 mg of material. Released to a specification of >99% purity by HPLC. Soluble in bacteriostatic water. Supplied for in-vitro laboratory research only. Not a drug, food or supplement. Not for human or veterinary use.
Volta does not provide dosing, administration or protocol guidance for any material listed.
Adamax Adamantane 10mg specifications
Every field the product record holds. A field with no value is omitted rather than printed as a dash.
- Fill
- 10mg
- Form
- Lyophilized powder
- Solubility
- Soluble in bacteriostatic water
- Shelf life
- 24 months from date of manufacture
Adamax Adamantane analytical verification and batch documentation
What the purity figure on this page is, who measured what, and which of the two a reader is looking at.
Specification. Every batch is released to >99% purity by HPLC. That is a threshold Volta sets, and it is a promise rather than a measurement.
Measurement. No certificate for this compound is published on the site yet. A batch-specific Certificate of Analysis is available on request, and the batch history lists the ones already published. Until one is published for this material, the figure above is the release specification and nothing on this page is a laboratory result.
Checking a certificate. The batch number printed beside the price is derived from the compound code and the vial strength; the lot number on a certificate is transcribed from the document. They are produced independently, so comparing them is a real check. How to read one is set out in the quality and testing methodology page.
For in-vitro laboratory research by qualified professionals only. Not for human or animal administration. Not a drug, food, cosmetic or dietary supplement. Not intended to diagnose, treat, cure, mitigate or prevent any disease.
The two Adamax grades in this catalogue differ in synthesis and purification rather than in sequence. Adamantane conjugation is the step where impurity profiles diverge most, because incomplete or double conjugation both produce species that co-elute closely with the target. This grade is intended for research where that impurity profile is itself a variable, such as structure-activity comparisons against unmodified Semax, and each lot ships with batch-specific HPLC and mass spectrometry documentation.
- Released to a >99% purity specification by HPLC
- Lyophilized powder, 10mg per vial
- Soluble in bacteriostatic water
- For laboratory research use only
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Adamax Adamantane 10mg: what is in the vial
The arithmetic specific to this 10mg vial, and what a milligram of Adamax Adamantane costs in each strength the catalogue carries. Concentrations are stated, not recommended.
Vial contents
10 mg
Lyophilised powder, reconstituted by the buyer
Cost of material
$16.50 / mg USD
CA$23.50 / mg in Canadian dollars
Concentration at each diluent volume
10 mg of dry material reaches these concentrations in the volumes below. A U-100 syringe marking is 0.01 ml by definition, so the last column is a unit conversion at each concentration rather than a quantity to use.
| Diluent added | Concentration | In 0.1 ml | Per U-100 unit |
|---|---|---|---|
| 1 ml | 10 mg/ml | 1 mg | 100 mcg |
| 2 ml | 5 mg/ml | 500 mcg | 50 mcg |
| 3 ml | 3.33 mg/ml | 333.3 mcg | 33.3 mcg |
| 5 ml | 2 mg/ml | 200 mcg | 20 mcg |
For a volume this table does not list, the reconstitution calculator takes any vial size and diluent volume.
Adamax Adamantane purity and identity: how the figure is measured
What >99% (HPLC) means, the masses an identity check has to land on, and the entries that make a certificate of analysis checkable rather than decorative.
Stated purity
>99% (HPLC)
Area percent of the main peak by reversed-phase HPLC
What a certificate for Adamax Adamantane should carry
A purity percentage on its own is not checkable. These are the entries that make one verifiable, and their absence is the most common weakness in a research-peptide certificate.
The chromatogram, not only the number
A stated area percent with no trace behind it cannot be read for the shape of the main peak or for what eluted beside it. The HPLC interpreter walks through what a trace shows.
Net peptide content, separately from gross mass
A lyophilised peptide is a salt, usually of trifluoroacetic or acetic acid, plus residual water. The vial's stated milligrams are gross; net peptide content is the fraction of that mass which is the molecule. The two differ by ten to twenty percent routinely, and only one of them is what the price is per milligram of. The net peptide content calculator converts between them.
The counterion, named
Which salt form the powder is in changes the net content and the pH the powder dissolves at. A certificate that never names it leaves both unknowable.
Water content, by a stated method
Loss on drying and Karl Fischer titration give different numbers, and a water figure with no method attached cannot be compared with anyone else's.
A laboratory and a report identifier
Without both, nothing on the document can be traced back to the laboratory that issued it. The red flag checker lists the rest.
Batch certificates are published as page images in the certificate library. The source PDFs are never served: a certificate is the most forgeable document a supplier publishes, and an editable copy carrying an accredited laboratory's letterhead is worth more to a counterfeiter than to a customer.
Adamax Adamantane storage and stability
Handling as the product record states it, followed by the degradation chemistry this particular sequence is and is not exposed to.
Handling
Store lyophilized peptide at -20°C in a dry, dark environment. Reconstitute in bacteriostatic water. Once reconstituted, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles. Lyophilized powder is stable at room temperature for shipping and short-term storage.
A residue-level stability profile needs a primary sequence of standard amino acids. This compound's sequence carries modified or non-standard residues, so no finding is derived for it rather than one being estimated from a partial reading. The storage guide covers the general case.
Adamax Adamantane compared with DSIP and Epithalon
Pharmacological class, half-life, evidence grade, competition status and cost per milligram, side by side.
| Compound | Class | Half-life | Evidence | WADA | Cheapest per mg |
|---|---|---|---|---|---|
| DSIP | Sleep / Neuropeptide | ~7–8 minutes IV; longer SC | DPreclinical | Not listed | $4.6710mg vial |
| Epithalon | Anti-Aging / Telomere | Several hours | DPreclinical | Not listed | $3.4010mg vial |
| HCG | Hormonal / Reproductive | ~24-36 hours | AFDA Approved | Not listed | — |
| KPV | Anti-Inflammatory / Immune | ~2 hours (SC); shorter oral due to GI degradation | DPreclinical | Not listed | $3.9010mg vial |
| MOTS-c | Metabolic / Mitochondrial | Several hours; tissue effects may persist longer | DPreclinical | Not listed | $3.2010mg vial |
Evidence grades and half-lives are as recorded in the compound database, which cites its own sources on each compound page. Per-milligram prices are the cheapest strength each compound is currently listed at, in US dollars, and an out-of-stock note means that figure is not purchasable today. Cross-trial comparisons of efficacy are not comparisons: no head-to-head trial exists for most of these pairs.
Adamax Adamantane in Canada
Price in Canadian dollars, where the parcel ships from, and how long it takes.
Price in CAD
CA$235
The figure charged, not a converted estimate
Ships from
British Columbia
A domestic parcel, so no import clearance step
Transit
2 to 5 business days
After 1 to 2 business days of handling
Free standard shipping
Over CA$250
A bar set for this market, not converted from the US one
Adamax Adamantane 10mg ships from British Columbia to Canadian addresses, so the parcel never crosses a border. That removes the failure a Canadian buyer of research peptides is usually weighing: an inbound international shipment can be held for import clearance or seized, and a domestic one has no clearance step to be held at.
Shipping is quoted live against the delivery address at checkout rather than estimated here, and both the standard and express tiers show their price and transit window before a payment method is chosen. The figure the page shows is the figure the rail charges: all three settlement rails price shipping through the same functions the quote does.
The Canadian figure above is not a loose conversion. Each product's US dollar base is chosen so that the live conversion lands on the Canadian shelf price set for this market, and the result is pushed up to a whole dollar rather than left carrying cents, so one figure serves the page, the feed and every payment rail. See the shipping policy for carriers and cut-off times, and the legal position on research peptides in Canada for the regulatory picture.
Adamax Adamantane Mechanism of Action
Chemically this is the same compound as Adamax: an adamantane-conjugated analogue of the ACTH(4-10) fragment, structurally related to Semax. The product listing is explicit that the two grades differ in synthesis and purification rather than in sequence, so any account of how this molecule works is the account given for Adamax.
The peptide portion derives from ACTH(4-10), the melanocortin fragment that Semax is also built on. The adamantyl group is a rigid lipophilic hydrocarbon cage conjugated to the peptide, intended to increase membrane permeability, which for a centrally aimed compound means improved access across the blood-brain barrier.
What distinguishes this listing is a claim about the conjugation step rather than about pharmacology. Adamantane conjugation is where impurity profiles diverge most, because incomplete or misplaced conjugation produces species that differ from the intended product in exactly the property the modification was meant to confer. A tighter specification on that step is a meaningful thing to offer, and it is a manufacturing claim that no published study can confirm or refute.
Same molecule as Adamax
The product listing states the two grades differ in synthesis and purification, not in sequence, so the pharmacology is identical by definition.
Parent fragment
Derived from ACTH(4-10), the melanocortin fragment Semax is built on, with the peptidase-resistant Pro-Gly-Pro extension.
Adamantane conjugation
A rigid lipophilic cage attached to the peptide, intended to increase membrane permeability and central access.
Conjugation as the impurity-critical step
Incomplete or misplaced conjugation yields species differing from the intended product precisely in the property the modification confers, which is why this step dominates the impurity profile.
Grade is a manufacturing claim
The difference offered here concerns lot-to-lot consistency of the conjugate, which is a claim about process control rather than about mechanism.
Semax and ACTH(4-10) Research Findings
No study below used this compound or the standard Adamax grade. They concern Semax, the parent analogue whose literature the mechanistic claims derive from.
Semax reported to regulate BDNF and TrkB expression
Work in rat hippocampus reported regulation of brain-derived neurotrophic factor and its receptor by the ACTH(4-10) analogue. Studied with Semax, not with any adamantane conjugate.
Rodent modelSpecific binding demonstrated in brain tissue
A study reported specific binding of the analogue in rat basal forebrain with increased BDNF protein, supporting a targeted interaction. Studied with Semax.
In vitroNeurotrophin transcripts induced rapidly in glial culture
Semax induced neurotrophin messenger RNAs in rat glial cultures on a short timescale, indicating an effect at the level of transcription. Studied with Semax.
In vitroThe glyproline fragment also activates neurotrophin transcription
Semax and Pro-Gly-Pro were both reported to activate transcription of neurotrophins, which implicates the shared tail as well as the parent sequence in the observed activity.
In vitroNo study distinguishes purity grades of this compound
The absence is worth recording explicitly. Since no published work has examined the compound at all, no evidence exists comparing a higher-specification preparation against a standard one.
ObservationalAdamax Adamantane Molecular Information
| Class | Adamantane-conjugated ACTH(4-10) fragment analogue |
| Relationship to Adamax | The same molecule. The listing states the grades differ in synthesis and purification, not in sequence |
| Parent Analogue | Semax, Met-Glu-His-Phe-Pro-Gly-Pro |
| Defining Modification | Adamantyl group, a rigid lipophilic hydrocarbon cage |
| Claimed Difference | Tighter purity and identity specification on the conjugation step |
| CAS Number | Not stated on the product listing |
| Molecular Formula | Not stated on the product listing |
| Molecular Weight | Not stated on the product listing |
| Appearance | White lyophilised powder |
The Difference Being Sold Is Process Control, Not Chemistry
This product and Adamax are the same molecule. The listing says so directly: the grades differ in synthesis and purification rather than in sequence. That means nothing in the pharmacology section can distinguish them, and a page implying otherwise would be misleading.
What is being offered is lot-to-lot consistency of the conjugate. For a conjugated peptide that is a substantive thing to offer rather than marketing, because conjugation is a step that can go incompletely or in the wrong place, and the resulting species are not simply inert filler.
The honest framing is that a purity grade claim is testable by analysis and not by literature. Whether it is true for any given lot is a question for the certificate, and no citation can answer it.
Why Conjugation Is the Impurity-Critical Step
Peptide synthesis impurities are usually truncations, deletions and oxidation products, all of which differ from the target in ways that analytical methods readily detect. Conjugation introduces a different class of problem.
An unconjugated peptide that survives purification is not a trace impurity: it is a molecule missing the entire feature the product exists to provide. A doubly conjugated species carries more of the lipophilic group than intended, with correspondingly different solubility and distribution. A conjugate attached at the wrong position has the right mass and the wrong structure, which mass spectrometry alone cannot distinguish.
That last case is why a tighter identity specification, not just a tighter purity figure, is the meaningful claim for a conjugated product, and it is what a buyer should be checking this grade against.
The Same Documentation Gap as the Standard Grade
Neither grade states a molecular weight, formula or CAS number. For a product whose selling point is the quality of a conjugation step, the absence of a stated conjugate mass is a particular problem, because that mass is the most direct evidence that conjugation occurred at all.
A grade claim without a stated target mass asks the buyer to accept a quality assertion about a step whose completion cannot be verified from the information provided. Requesting the conjugate mass and the retention behaviour against the unmodified parent is the reasonable response.
There is no approval for this compound in any jurisdiction and no human data. Material supplied for research is for in-vitro laboratory use only.
Handling and Analytical Considerations
Handling is identical to the standard grade, because the molecule is identical. The adamantyl group reduces aqueous solubility relative to the unmodified peptide and may require a co-solvent, and it increases reversed-phase retention substantially.
That retention shift is the practical test worth running on either grade. A conjugated product elutes markedly later than unmodified Semax; a preparation eluting at the parent's retention time contains parent peptide, whatever the label says about specification.
Adamax Adamantane Research FAQ
Adamax Adamantane in Summary
This is the same adamantane-conjugated ACTH(4-10) analogue as Adamax, offered at a tighter purity and identity specification. The difference is process control rather than chemistry, so no pharmacological claim can distinguish the two grades.
For a conjugated peptide a grade claim is substantive, because conjugation can be incomplete, doubled or misplaced. But neither grade states a conjugate mass, which is the most direct evidence that conjugation occurred at all.
Scientific References
Primary literature and public trial registries only. No supplier or retailer pages are cited.
This is the same molecule as Adamax at a tighter purity specification, so it has the same literature: none. Searching PubMed for the compound returns nothing, and no study distinguishes purity grades of it because no study has examined it at all. The references below are the Semax literature, cited because the peptide portion derives from that parent analogue. A grade difference is a manufacturing claim rather than a pharmacological one, and no citation can support it.
- 1Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampusDolotov OV, Karpenko EA, Inozemtseva LS, et al. · Brain Research · 2006
- 2Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrainDolotov OV, Karpenko EA, Seredenina TS, et al. · Journal of Neurochemistry · 2006
- 3Rapid induction of neurotrophin mRNAs in rat glial cell cultures by Semax, an adrenocorticotropic hormone analogShadrina MI, Dolotov OV, Grivennikov IA, et al. · Neuroscience Letters · 2001
- 4Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemiaStavchansky VV, Yuzhakov VV, Botsina AY, et al. · Cellular and Molecular Neurobiology · 2010
Disclaimer
All articles and product information provided on this website are for informational and educational purposes only. The products offered on this website are furnished for in-vitro studies only. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease.
Adamax Adamantane 10mg: frequently asked questions
Answered from the product record and the certificate file. Volta does not answer questions about administration, dosing or protocols.
What is supplied in a 10 mg vial of Adamax Adamantane?
A sealed single-use vial containing 10 mg of Adamax Adamantane as a lyophilized powder. Soluble in bacteriostatic water. No diluent, syringe or other supply is included.
Is Adamax Adamantane supplied for human use?
No. For in-vitro laboratory research by qualified professionals only. Not for human or animal administration. Not a drug, food, cosmetic or dietary supplement. Not intended to diagnose, treat, cure, mitigate or prevent any disease. Volta does not provide dosing, administration or protocol guidance for any material listed.
What purity is this Adamax Adamantane released to?
>99% by HPLC. That figure is a release specification, a threshold Volta sets for every batch, and it is not the same kind of statement as a purity measured by a named laboratory for a named lot.
Is there a certificate of analysis for this Adamax Adamantane vial?
A batch-specific Certificate of Analysis is available for this product on request. It is not published on the site yet: the batch history on the quality page lists the certificates already published, and this vial is covered by the release specification until its own is added there.
How should Adamax Adamantane be stored before reconstitution?
Store lyophilized peptide at -20°C in a dry, dark environment. Reconstitute in bacteriostatic water. Once reconstituted, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles. Lyophilized powder is stable at room temperature for shipping and short-term storage.
Where does this ship from?
British Columbia, Canada. Canadian orders are domestic, so they clear no customs and pay no import duty. International orders ship from the same facility.
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