Peptides for Hair Growth
Comprehensive guide to 7 peptides researched for hair growth, ranked by evidence strength from FDA-approved to early preclinical. Each compound is evaluated on mechanism, clinical status, and safety profile.
Overview
7 research peptides are currently studied for hair growth. This guide ranks them by evidence strength and covers their mechanisms, safety profiles, and current clinical status.
AHK (Ala-His-Lys) — Preclinical Only
Evidence Rating: D
Category: Cosmetic / Research
AHK (Alanyl-Histidyl-Lysine) is a tripeptide related to GHK that shares copper-binding properties. It has been studied for its ability to stimulate hair follicle growth and promote wound healing through collagen synthesis and growth factor upregulation. Evidence is limited to in vitro studies and an...
Key claims: Stimulates hair growth; Promotes wound healing.
AHK-Cu (Copper AHK) — Preclinical Only
Evidence Rating: D
Category: Cosmetic / Research
AHK-Cu is the copper-complexed form of the AHK tripeptide. The addition of copper enhances its biological activity, particularly in stimulating dermal papilla cells for hair growth and wound healing applications. Used in topical cosmetic formulations.
Key claims: Superior hair growth stimulation vs AHK alone.
PTD-DBM — Preclinical
Evidence Rating: D
Category: Hair Growth
PTD-DBM is a cell-permeable peptide that activates the Wnt/β-catenin signaling pathway, a key regulator of hair follicle development and cycling. In preclinical studies, topical application of PTD-DBM promoted new hair growth in mice by stimulating dermal papilla cells. It represents a novel peptide...
Key claims: Stimulates new hair follicle growth; Activates dermal papilla cells.
Acetyl Tetrapeptide-3 — Manufacturer-Sponsored Studies
Evidence Rating: D
Category: Hair Growth / Cosmetic
Acetyl Tetrapeptide-3 is a biomimetic cosmetic peptide used in hair care formulations, most notably as the peptide component of Capixyl (combined with red clover-derived biochanin A). Manufacturer-sponsored studies report a 17% increase in hair diameter and 46% reduction in hair loss at 12 weeks of ...
Key claims: Increases hair diameter by 17%; Reduces hair loss by 46%.
Astressin-B — Preclinical / Serendipitous Finding
Evidence Rating: D
Category: Stress / CRF Antagonist
Astressin-B is a synthetic cyclic peptide antagonist of corticotropin-releasing factor (CRF) receptors, originally developed for stress-related research. It gained viral attention after a 2011 Salk Institute study showed that a single injection reversed hair loss in chronically stressed mice. The ha...
Key claims: Reverses stress-induced hair loss in mice; Blocks CRF-mediated stress response.
Myristoyl Pentapeptide-17 — No Regulatory Activity
Evidence Rating: F
Category: Cosmetic Peptide
Myristoyl pentapeptide-17 is a lipopeptide used in eyelash and eyebrow growth cosmetic products. It is proposed to promote hair growth by stimulating keratin gene expression in hair follicle cells. The myristoyl (C14 fatty acid) chain enhances follicular penetration. Clinical evidence is very limite...
Key claims: Promotes eyelash and eyebrow growth; Stimulates keratin production.
Biotinoyl Tripeptide-1 — No Regulatory Activity
Evidence Rating: F
Category: Cosmetic Peptide
Biotinoyl tripeptide-1 is a peptide consisting of the GHK (glycyl-histidyl-lysine) tripeptide conjugated to biotin (vitamin B7). It is used in hair care products, often as part of the Procapil complex (biotinoyl tripeptide-1 + apigenin + oleanolic acid). It is designed to strengthen hair and reduce ...
Key claims: Reduces hair loss; Strengthens hair.
Shop Research Peptides
Retatrutide 20mg
20mg
BPC-157 5mg
5mg
Ipamorelin 10mg
10mg
Semaglutide 10mg
10mg
TB-500 5mg
5mg
Retatrutide 10mg
10mg
GHK-Cu 50mg
50mg
Sermorelin 5mg
5mg
Tesamorelin 10mg
10mg
Quality Documentation
Review batch documentation before making research purchasing decisions. Volta pairs product education with COA literacy so researchers can evaluate purity, identity, lot details, and testing context.
Product cards on this page link to current catalog entries and available quality documentation.
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