Metabolic / Dual GLP-1/Glucagon Agonist Research Peptides Guide
In-depth research guide covering 3 peptides in the Metabolic / Dual GLP-1/Glucagon Agonist category. Includes evidence ratings, mechanisms, and clinical status for each compound.
Overview
This guide covers 3 research peptides in the Metabolic / Dual GLP-1/Glucagon Agonist category. Each compound is evaluated on its evidence base, mechanism, safety profile, and current clinical status.
Mazdutide — Phase I–II Clinical Trials
Evidence: C | Status: Approved in China (June 2024) for chronic weight management. Phase III in China for T2D. Not yet approved outside China.
Mazdutide (IBI362) is a dual GLP-1/glucagon receptor agonist co-developed by Innovent Biologics and Eli Lilly (MW ~4233.7 g/mol).
Use cases: Weight Management, Metabolic Health
Pemvidutide — Phase I–II Clinical Trials
Evidence: C | Status: Phase II completed (MOMENTUM for obesity, IMPACT for NASH/MASH). Phase III anticipated.
Pemvidutide (ALT-801) is a dual GLP-1/glucagon receptor agonist being developed by Altimmune for the treatment of obesity and nonalcoholic steatohepatitis (NASH/MASH).
Use cases: Weight Management, Metabolic Health
Cotadutide — Phase I–II Clinical Trials
Evidence: C | Status: Phase II completed for T2D, obesity, and NASH/MASH. Development status uncertain; AstraZeneca has not advanced to Phase III.
Cotadutide (MEDI0382) is a dual GLP-1/glucagon receptor agonist developed by AstraZeneca (originally MedImmune). It is a once-daily injectable peptide designed to combine GLP-1 receptor-mediated glucose lowering and appetite suppression with...
Use cases: Metabolic Health, Weight Management
Shop Research Peptides
Retatrutide 20mg
20mg
BPC-157 5mg
5mg
Ipamorelin 10mg
10mg
Semaglutide 10mg
10mg
TB-500 5mg
5mg
Retatrutide 10mg
10mg
GHK-Cu 50mg
50mg
Sermorelin 5mg
5mg
Tesamorelin 10mg
10mg
Quality Documentation
Review batch documentation before making research purchasing decisions. Volta pairs product education with COA literacy so researchers can evaluate purity, identity, lot details, and testing context.
Product cards on this page link to current catalog entries and available quality documentation.
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