oligonucleotides
3 articles tagged with ‘oligonucleotides’
High-Purity Nucleic Acid Amidites and Amino Acid Building Blocks
Research platforms supply high-quality building blocks for nucleic acids, peptides, and conjugates from discovery to commercial stages. These include extensive catalogs of amidites, nucleotides, and modified amino acids with purity levels exceeding 99%. Specific products feature detailed molecular formulas, CAS numbers, and categories for oligonucleotide and peptide synthesis support.
Oligonucleotide Drug Product Development and Manufacturing
Facilities support parenteral drug product development and manufacturing for oligonucleotide drugs from preclinical to commercial stages. Teams handle 85,000+ characterization tests yearly across 5 production lines with 70 million units annual capacity. Services cover advanced formulations like lipid nanoparticles, high potency injectables, and clinical supplies for phases I to IV.
Oligonucleotide CRDMO Platform: Discovery to Commercial Manufacturing
This platform delivers full CRDMO services for oligonucleotides, covering discovery synthesis at nmol-mmol scales up to mol-scale commercial production. It includes monomers, linkers, ligands, conjugates, formulation, analytical testing, and CMC dossier preparation under a single quality system. Capabilities span DNA, ASOs, siRNAs, and more, with global regulatory approvals from FDA, EMA, and others.