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Determine which solvents are safe for dissolving specific peptide types based on their properties.
Standard for multi-use vials, preservative
Concentration: 0.9% benzyl alcohol
Physiological buffer, good general choice
Concentration: pH 7.4, 10mM
Isotonic, injection-ready
Concentration: 0.9% NaCl
General-purpose for hydrophilic peptides
Concentration: As needed
Good for basic and hydrophobic peptides
Concentration: 0.1% (v/v)
For acidic peptides that need basic pH
Concentration: 0.1M NaHCO₃
Last resort for very hydrophobic peptides
Concentration: 100% or dilute to <10%
⚠ Cytotoxic at high concentrations — dilute before use
General guidance only. Always verify solubility with small test amounts first. Solubility depends on concentration, pH, temperature, and specific peptide sequence. Not medical advice.