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IGF-1 LR3 vs MGF
Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.
IGF-1 LR3: DMGF: D
| Attribute | IGF-1 LR3 | MGF |
|---|---|---|
| Category | Growth Factor | Growth Factor |
| Evidence Rating | D — Preclinical | D — Preclinical |
| Clinical Status | No clinical trials for therapeutic use. Research compound only. | Preclinical only. No human clinical trials. |
| Mechanism | IGF-1 LR3 binds to IGF-1 receptors on target cells with high affinity, initiating tyrosine kinase signaling that activates the PI3K/Akt/mTOR pathway, increasing protein synthesis, glucose uptake, and cellular survival while inhibiting muscle protein breakdown (anti-catabolic). Its low affinity for I... | MGF is expressed as part of the IGF-1 gene through alternative splicing in response to mechanical overload or tissue damage. The E-domain peptide (distinct from the mature IGF-1 peptide) activates satellite cells — muscle stem cells that donate nuclei to growing or repairing muscle fibers. It upregu... |
| Half-Life | 20-30 hours | Minutes (non-PEGylated); rapidly degraded by serum proteases |
| Bioavailability | — | — |
| Molecular Weight | ~9,111 g/mol (9.1 kDa) | — |
| WADA Status | Prohibited | Prohibited |
| Research Half-Life | 20-30 hours | Minutes (non-PEGylated); rapidly degraded by serum proteases |
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| Regulatory (US) | Not FDA-approved. Research chemical only. WADA-banned (S2 growth factors). | Not FDA-approved. Research chemical only. WADA-banned. |
Research Material Specifications
Catalog specifications for the corresponding research materials, including batch documentation coverage.
| Specification | IGF-1 LR3 | MGF |
|---|---|---|
| Purity Standard | ≥98% | ≥98% |
| CAS Number | N/A | N/A |
| Molecular Formula | N/A | N/A |
| Available Formats | 1mg | 2mg |
| Batch COAs Published | — | — |
| Stock Status | Out of stock | Out of stock |
Availability at Volta Peptides
Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.
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