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All Comparisons

GHRP-2 vs Tesamorelin

Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.

GHRP-2: CTesamorelin: A
AttributeGHRP-2Tesamorelin
CategoryGrowth Hormone SecretagogueGrowth Hormone Secretagogue
Evidence RatingC — Phase I–II Clinical TrialsA — FDA Approved
Clinical StatusApproved in Japan for GH deficiency diagnosis; research-only elsewhereFDA-approved (Egrifta SV 2019, Egrifta WR March 2025) for HIV-associated lipodystrophy
MechanismGHRP-2 (C45H55N9O6) binds to and activates ghrelin (GH secretagogue) receptors on pituitary somatotrophs, triggering robust pulsatile GH release. In healthy adults, 100 mcg SC daily produces acute GH stimulation. Unlike continuous GH, GHRP-2 maintains physiological feedback controls. Once-daily admi...Tesamorelin binds to and stimulates human GRF (growth hormone-releasing factor) receptors on the anterior pituitary with similar potency as endogenous GRF, stimulating synthesis and release of endogenous growth hormone. This increases IGF-1 and IGFBP-3 levels, leading to increased lipolysis and redu...
Half-Life~15–60 minutes~26–38 minutes
Bioavailability——
Molecular Weight~817.0 g/mol~5135.9 g/mol
WADA StatusProhibitedProhibited
Research Half-Life~15–60 minutes~26–38 minutes
Key Use Cases
  • Body Composition
  • Body Composition
Safety Concerns
  • Well tolerated in clinical trials with placebo-like safety profile at therapeutic ranges
  • May increase appetite (less than GHRP-6)
  • Can elevate cortisol and prolactin levels (less than GHRP-6)
  • Common: injection site reactions (17%), arthralgia (13%), myalgia (6%), peripheral edema (6%)
  • Headache, nausea, and flu-like symptoms reported
  • May increase blood glucose -- monitoring recommended in diabetics
Contraindications
  • Active malignancy (GH/IGF-1 elevation contraindicated)
  • Pregnancy and breastfeeding
  • Pituitary disorders (outside diagnostic context)
  • Diabetes and cardiovascular conditions (GH affects glucose metabolism)
  • Pregnancy (Category X -- absolute contraindication)
  • Active cancer or history of any tumor (benign or malignant)
  • Pituitary gland disorder, tumor, or history of pituitary surgery
  • History of head injury or radiation treatment to the head
Regulatory (US)Not FDA-approved. Research chemical only. Banned by WADA.FDA-approved: Egrifta SV (Oct 2019) and Egrifta WR (March 2025) for HIV-associated lipodystrophy. Prescription only.

Research Material Specifications

Catalog specifications for the corresponding research materials, including batch documentation coverage.

SpecificationGHRP-2Tesamorelin
Purity Standard>99%>99%
CAS Number158861-67-7218949-48-5
Molecular FormulaC₄₅H₅₅N₉O₆C₂₂₃H₃₇₀N₇₂O₆₉S
Available Formats5mg, 10mg10mg, 20mg, 10mg
Batch COAs Published—1 on file
Stock StatusIn stockIn stock

Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.

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