GHRP-2 vs Ipamorelin
Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.
| Attribute | GHRP-2 | Ipamorelin |
|---|---|---|
| Category | Growth Hormone Secretagogue | Growth Hormone Secretagogue |
| Evidence Rating | C — Phase I–II Clinical Trials | D — Preclinical |
| Clinical Status | Approved in Japan for GH deficiency diagnosis; research-only elsewhere | Research-only / Not approved for human use |
| Mechanism | GHRP-2 (C45H55N9O6) binds to and activates ghrelin (GH secretagogue) receptors on pituitary somatotrophs, triggering robust pulsatile GH release. In healthy adults, 100 mcg SC daily produces acute GH stimulation. Unlike continuous GH, GHRP-2 maintains physiological feedback controls. Once-daily admi... | Ipamorelin (sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2) selectively binds to the Growth Hormone Secretagogue Receptor (GHS-R1a) on anterior pituitary somatotroph cells, increasing cAMP and activating protein kinase A to promote pulsatile GH secretion. Its structural specificity means it fits only the GH... |
| Half-Life | ~15–60 minutes | ~2 hours |
| Bioavailability | — | High SC bioavailability |
| Molecular Weight | ~817.0 g/mol | ~711.9 g/mol |
| WADA Status | Prohibited | Prohibited |
| Research Half-Life | ~15–60 minutes | ~2 hours |
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| Regulatory (US) | Not FDA-approved. Research chemical only. Banned by WADA. | Not FDA-approved. Research chemical only. WADA-banned (S2 growth factor). |
Research Material Specifications
Catalog specifications for the corresponding research materials, including batch documentation coverage.
| Specification | GHRP-2 | Ipamorelin |
|---|---|---|
| Purity Standard | ≥98% | ≥98% |
| CAS Number | 158861-67-7 | 170851-70-4 |
| Molecular Formula | N/A | C₃₈H₄₉N₉O₅ |
| Available Formats | 10mg | 10mg, 10mg, 20mg, 10mg |
| Batch COAs Published | — | 2 on file |
| Stock Status | Out of stock | In stock |
Availability at Volta Peptides
Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.
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