pal-ahk

Pal-AHK's Role in Follicular Cell Growth and Apoptosis Reduction

Pal-AHK, a palmitoylated tripeptide of alanine-histidine-lysine, shows potential in modulating dermal papilla cells central to hair follicle regulation. Studies indicate it reduces apoptosis in these cells by 3.48% and lowers active caspase-3 by 42.7%, alongside boosting collagen production by 300% in fibroblasts. These effects stem from copper binding and shifts in growth factors like VEGF and TGF-β1.