biomedical-research
2 articles tagged with ‘biomedical-research’
Cell-Penetrating Peptides Aid Intracellular Delivery
Over the last decade, researchers have studied cell-penetrating peptides for delivering cargoes across cell membranes. These peptides carry low molecular weight drugs, imaging agents, peptides, oligonucleotides, proteins, and carriers like liposomes and polymeric nanoparticles. Their non-toxic membrane crossing boosts drug bioavailability, though uptake mechanisms remain unclear.
Special Antigen Peptides in Vaccines and Immunotherapy
Special antigen peptides, short amino acid chains of 5 to 50 residues, mimic protein epitopes from diseases like infections, cancers, and autoimmune conditions. They drive immune responses in vaccine development, immunotherapy, and diagnostics without causing illness. Design involves bioinformatics for epitope selection, optimization for stability, and synthesis methods like solid-phase techniques.