All Comparisons
Thymosin Alpha-1 vs Thymalin
Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.
Thymosin Alpha-1: CThymalin: C
| Attribute | Thymosin Alpha-1 | Thymalin |
|---|---|---|
| Category | Immune Modulator | Immune / Anti-Aging |
| Evidence Rating | C — Phase I–II Clinical Trials | C — Early Human or Mixed Evidence |
| Clinical Status | Approved in 35+ countries (Zadaxin); FDA orphan drug designation; not FDA-approved in the US | Approved medication in Russia for immunodeficiency. Used clinically since 1982. Western clinical evidence is limited. |
| Mechanism | Ta1 (C129H215N33O55) activates Toll-like Receptors TLR2 and TLR9 on immune cells, triggering the MyD88 and NF-kB signaling pathways to put the immune system on alert without destructive inflammation. Key mechanism: increases MHC Class I expression, unmasking hidden viruses and cancer cells for immun... | Thymalin contains short bioregulatory peptides (primarily di- and tripeptides including Glu-Trp) derived from thymic tissue. These peptides are proposed to interact with DNA regulatory sequences, modulating gene expression related to immune function. Specifically, thymalin is thought to promote thym... |
| Half-Life | ~2 hours | ~30-60 minutes (short peptide complex) |
| Bioavailability | — | ~100% IM/SC |
| Molecular Weight | ~3108.3 g/mol | — |
| WADA Status | Prohibited | Not Listed |
| Research Half-Life | ~2 hours | ~30-60 minutes (short peptide complex) |
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| Regulatory (US) | Not FDA-approved. FDA orphan drug designation for hepatitis B. Available through compounding pharmacies. | Not FDA-approved. Available as research peptide. |
Research Material Specifications
Catalog specifications for the corresponding research materials, including batch documentation coverage.
| Specification | Thymosin Alpha-1 | Thymalin |
|---|---|---|
| Purity Standard | ≥98% | ≥98% |
| CAS Number | 62304-98-7 | N/A |
| Molecular Formula | N/A | N/A |
| Available Formats | 10mg | 10mg |
| Batch COAs Published | — | — |
| Stock Status | Out of stock | Out of stock |
Availability at Volta Peptides
Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.
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