All Comparisons
Hexarelin vs Ipamorelin
Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.
Hexarelin: CIpamorelin: D
| Attribute | Hexarelin | Ipamorelin |
|---|---|---|
| Category | Growth Hormone Secretagogue | Growth Hormone Secretagogue |
| Evidence Rating | C — Phase I–II Clinical Trials | D — Preclinical |
| Clinical Status | Phase II completed. Development discontinued due to tolerance/desensitization concerns. | Research-only / Not approved for human use |
| Mechanism | Hexarelin binds to and activates the ghrelin/growth hormone secretagogue receptor (GHS-R1a) in the pituitary and hypothalamus through a triple mechanism: direct stimulation of pituitary somatotroph cells to release stored GH, stimulation of hypothalamic GHRH-releasing neurons, and suppression of som... | Ipamorelin (sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2) selectively binds to the Growth Hormone Secretagogue Receptor (GHS-R1a) on anterior pituitary somatotroph cells, increasing cAMP and activating protein kinase A to promote pulsatile GH secretion. Its structural specificity means it fits only the GH... |
| Half-Life | ~70 minutes | ~2 hours |
| Bioavailability | — | High SC bioavailability |
| Molecular Weight | ~887 g/mol | ~711.9 g/mol |
| WADA Status | Prohibited | Prohibited |
| Research Half-Life | ~70 minutes | ~2 hours |
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| Regulatory (US) | Not FDA-approved. Development discontinued. Research chemical only. | Not FDA-approved. Research chemical only. WADA-banned (S2 growth factor). |
Research Material Specifications
Catalog specifications for the corresponding research materials, including batch documentation coverage.
| Specification | Hexarelin | Ipamorelin |
|---|---|---|
| Purity Standard | ≥98% | ≥98% |
| CAS Number | 140703-51-1 | 170851-70-4 |
| Molecular Formula | N/A | C₃₈H₄₉N₉O₅ |
| Available Formats | 5mg | 10mg, 10mg, 20mg, 10mg |
| Batch COAs Published | — | 2 on file |
| Stock Status | Out of stock | In stock |
Availability at Volta Peptides
Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.
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