All Comparisons
GHK-Cu vs AHK-Cu (Copper AHK)
Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.
GHK-Cu: FAHK-Cu (Copper AHK): D
| Attribute | GHK-Cu | AHK-Cu (Copper AHK) |
|---|---|---|
| Category | Skin & Tissue Repair | Cosmetic / Research |
| Evidence Rating | F — No Regulatory Activity | D — Preclinical Only |
| Clinical Status | Available in cosmetic formulations; no drug approval | Research-only |
| Mechanism | GHK-Cu chelates copper(II) ions via its histidine residue and delivers bioavailable copper directly to cells, preventing free copper oxidative damage. It stimulates collagen, elastin, and glycosaminoglycan synthesis, modulates metalloproteinases (MMPs) and their tissue inhibitors (TIMPs), attracts i... | Copper-dependent enzyme activation enhances dermal papilla cell stimulation. The copper complex promotes angiogenesis and ECM remodeling, with enhanced bioactivity compared to the non-copper form. |
| Half-Life | ~30 minutes plasma | — |
| Bioavailability | — | Topical only |
| Molecular Weight | ~403.9 g/mol | ~417.9 g/mol (copper complex) |
| WADA Status | Not Listed | Not Listed |
| Research Half-Life | ~30 minutes plasma | — |
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| Regulatory (US) | Available as a cosmetic ingredient (Copper Tripeptide-1). Not FDA-approved as a drug. Removed from FDA Category 2 on April 15, 2026 after HHS Secretary Kennedy directed withdrawal of nominations. PCAC review scheduled July 23-24, 2026. No IND application filed for injectable use. | — |
Research Material Specifications
Catalog specifications for the corresponding research materials, including batch documentation coverage.
| Specification | GHK-Cu | AHK-Cu (Copper AHK) |
|---|---|---|
| Purity Standard | >99% | >99% |
| CAS Number | 89030-95-5 | — |
| Molecular Formula | C₁₄H₂₂CuN₆O₄ | — |
| Available Formats | 50mg, 100mg | 100mg |
| Batch COAs Published | 1 on file | — |
| Stock Status | In stock | Out of stock |
Availability at Volta Peptides
Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.
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