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igf-2

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RegulatoryMay 12, 2026

Insulin-Like Growth Factors: IGF-1 and IGF-2 Explained

Insulin-like growth factors IGF-1 and IGF-2 play key roles in growth and development. IGF-1, stimulated by growth hormone, rises 2-3 fold during puberty and acts as both endocrine and local growth factors. IGF-2 supports fetal growth and binds distinct receptors, influencing proliferation and survival.

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