clinical-trials
2 articles tagged with ‘clinical-trials’
Aclerastide: Effective Therapy for Diabetic Foot Ulcers
Aclerastide, an analog of angiotensin 1-7, shows strong potential in treating diabetic foot ulcers through progenitor proliferation, vascularization, collagen deposition, and re-epithelialization. Preclinical studies demonstrate its superiority over existing topical growth factors, with Phase II trials confirming faster wound closure lasting up to 20 weeks. Phase III trials are now recruiting patients.
Retatrutide Dosing Guide: Schedules, Safety, and Weight Loss Results
Retatrutide, a triple agonist targeting GLP-1, GIP, and glucagon receptors, produced mean weight reductions approaching 24% of baseline body weight after 48 weeks at the highest doses in phase 2 trials. Clinical studies tested weekly doses from 1 mg to 12 mg with gradual titration to improve tolerability and reduce gastrointestinal side effects. This guide covers dosing protocols, progression impacts, and key trial data for the experimental obesity treatment.