cell-penetrating-peptides
2 articles tagged with ‘cell-penetrating-peptides’
Cell-Penetrating Peptides Aid Intracellular Delivery
Over the last decade, researchers have studied cell-penetrating peptides for delivering cargoes across cell membranes. These peptides carry low molecular weight drugs, imaging agents, peptides, oligonucleotides, proteins, and carriers like liposomes and polymeric nanoparticles. Their non-toxic membrane crossing boosts drug bioavailability, though uptake mechanisms remain unclear.
Classes and Applications of Cell-Penetrating Peptides
Cell-penetrating peptides fall into categories like cationic, amphiphilic, and hydrophobic based on properties, with cationic and amphiphilic types making up 85%. Examples include TAT and Penetratin for cationic ones. These peptides aid tumor treatment, siRNA delivery, and inflammation therapy through specific mechanisms and studies.