GLP-1 LR in Canada
Peptides
GLP-1 LR is not in the catalogue yet. When it ships it will be dispatched from British Columbia, so Canadian orders clear no customs and cross no border. Add your email below and you will hear the day it is available.
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About GLP-1 LR
GLP-1 LR is an acylated analogue of human GLP-1(7-37) with 97% amino acid sequence homology to the native peptide. Lysine 34 is replaced by arginine, and a C16 palmitoyl chain is attached to lysine 26 through a glutamic acid spacer.
Mechanism
GLP-1 LR is an agonist at the GLP-1 receptor, a Gs-coupled class B GPCR, and its activation is read out as cAMP accumulation in receptor-expressing cells. The palmitoyl side chain binds serum albumin non-covalently and promotes self-association, which slows DPP-4 cleavage relative to native GLP-1. It is the shorter-acting predecessor of GLP-1 SM, which carries a longer fatty diacid and an Aib substitution at position 8.
In the meantime
Research use only
This product is not a drug, food, or cosmetic, and is not for human consumption.
Products are sold only to qualified researchers and licensed laboratories.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Volta Peptides supplies materials strictly for in-vitro laboratory research. Nothing on this page is a drug, supplement, cosmetic or food, and nothing here is intended for human or animal use, clinical application or diagnostic procedures. The research summary above describes published literature and is not a claim of therapeutic benefit or a statement that this compound is offered for such use.