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Quality

As-Received Basis

Definition

A result calculated on the material exactly as it arrived, water and counterion included. It is the honest basis for what is in the vial and reads lower than the same measurement on a dry basis.

In more detail

A result on an as-received basis is calculated on the material exactly as it arrived, water and counterion included. It is the honest description of what is in the container.

It reads lower than the same measurement expressed on an anhydrous basis, and the gap is not small for a lyophilised peptide, where water and trifluoroacetate together can account for a noticeable share of the mass. Two certificates can disagree by several percent while both are correct, purely because one states a basis and the other states a different one.

Terms used in this definition

Other entries this definition refers to.

What this means for research sourcing

Purity and identity verification are central to research reproducibility. Every Volta compound ships with >99% HPLC-verified purity and a certificate of analysis.

Related Terms in Quality

Anhydrous Basis

A result recalculated as though the water content had been removed, using a separately measured water figure. Two certificates can disagree by several percent purely because one reports anhydrous and the other as received.

Not Detected (ND)

The analyte produced no signal distinguishable from background at the method's limit of detection. It states the limit of what was looked for, not that the substance is absent.

Not Less Than (NLT)

A one-sided specification setting a floor. Purity written as NLT 99.0% is met at 99.0 and failed at 98.9, and nothing above the floor is more compliant than anything else above it.

Not More Than (NMT)

A one-sided specification setting a ceiling, used for things wanted low: single impurities, water content, residual solvents, endotoxin. The pair NLT and NMT is how most certificates express a range.

Specification

The full set of tests and acceptance criteria a material must meet to be released, agreed before manufacture. A certificate reports results; the specification is what makes those results a pass or a fail.

Lot Number

The identifier tying material in a container to the records of how it was made and tested. It is the one field that lets a vial in somebody's hand be matched to the certificate that describes it.

Sample Identification

The unique reference a laboratory assigns to what it received, distinct from the lot number the supplier assigned. A certificate carrying both is traceable from the vial to the bench and back.

Pooled Sample

Material combined from several containers and tested as one. It reports the average and hides variation between them, so a pooled result says less about any individual vial than its purity figure suggests.

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