Acetyl Hexapeptide-8
Definition
The INCI name for the six-residue sequence marketed as Argireline. Acetyl hexapeptide-3 appears in older listings for the same material, so two names in a label archive do not mean two ingredients.
Terms used in this definition
Other entries this definition refers to.
Where this term comes up
Entries whose definition mentions Acetyl Hexapeptide-8.
What this means for research sourcing
Structure and identity terms are what a certificate of analysis is written in. Every Volta compound ships with its sequence, molecular weight and measured purity, so these terms map directly onto the specification on the product page.
Related Terms in Chemistry & Structure
Palmitoyl Pentapeptide-4
The INCI name for the palmitoylated five-residue sequence sold as Matrixyl. The palmitoyl group is a lipid tail added to help a hydrophilic peptide associate with the stratum corneum.
Bioactive Peptide
A peptide that produces a measurable response in living cells, as distinct from one that is merely present. The term is used loosely across food science, cosmetics and pharmacology, so it carries no implication about how strong the evidence is.
Peptide Hormone
A peptide the body releases into circulation to act on distant tissue. Insulin, glucagon, growth hormone and GLP-1 are all peptide hormones, and most of the metabolic research compounds in this field are analogues of one of them.
Mitochondrial-Derived Peptide
A short peptide encoded within mitochondrial DNA rather than in the nucleus, MOTS-c and humanin being the best known. Their existence is why the mitochondrial genome is now discussed as a signalling genome and not only a respiratory one.
Signal Peptide (Targeting Sequence)
A short stretch at the start of a newly made protein that routes it to the right compartment and is then cleaved off. It is unrelated to a signaling peptide, which is a finished molecule that carries a message between cells; the two terms are a standing source of confusion.
Dalton (Da)
The unit of molecular mass, one twelfth the mass of a carbon-12 atom. Peptides are quoted in daltons and proteins usually in kilodaltons, and the figure on a certificate is the monoisotopic or average mass depending on the method.
Isomer
A compound with the same molecular formula as another but a different arrangement of atoms. Isomers share a mass, so mass spectrometry alone cannot separate them and chromatography or a chiral method is required.
Molecular Formula
The count of each element in one molecule, written as a string such as C221H342N46O68. It fixes the molecular mass exactly, which is why a formula and a stated mass that disagree indicate an error in one of them.