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All Comparisons

CJC-1295 vs GHRP-2

Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.

CJC-1295: DGHRP-2: C
AttributeCJC-1295GHRP-2
CategoryGrowth Hormone SecretagogueGrowth Hormone Secretagogue
Evidence RatingDPreclinicalCPhase I–II Clinical Trials
Clinical StatusResearch-only / Not approved for human useApproved in Japan for GH deficiency diagnosis; research-only elsewhere
MechanismCJC-1295 binds to GHRH receptors (GHRHR) on pituitary somatotroph cells, activating intracellular cAMP signaling to stimulate both the transcription of the GH gene and pulsatile release of endogenous growth hormone, which in turn increases IGF-1 levels. The released IGF-1 travels to muscle tissue fo...GHRP-2 (C45H55N9O6) binds to and activates ghrelin (GH secretagogue) receptors on pituitary somatotrophs, triggering robust pulsatile GH release. In healthy adults, 100 mcg SC daily produces acute GH stimulation. Unlike continuous GH, GHRP-2 maintains physiological feedback controls. Once-daily admi...
Half-LifeNo DAC (mod GRF 1-29): ~30 min; With DAC: ~8 days~15–60 minutes
Bioavailability
Molecular WeightNo DAC: ~3367.9 g/mol; With DAC: ~3647.3 g/mol~817.0 g/mol
WADA StatusProhibitedProhibited
Research Half-LifeNo DAC (mod GRF 1-29): ~30 min; With DAC: ~8 days~15–60 minutes
Key Use Cases
  • Anti-Aging
  • Body Composition
  • Body Composition
Safety Concerns
  • Common: transient flushing/"head rush" within 5-10 minutes post-injection — hallmark of a potent injection, harmless and brief
  • Self-reported: flu-like symptoms, headaches, irritability, anxiety, nausea, hives (mild and transient)
  • Water retention and edema (dose-dependent; elevated GH causes sodium/water retention via kidneys)
  • Well tolerated in clinical trials with placebo-like safety profile at therapeutic ranges
  • May increase appetite (less than GHRP-6)
  • Can elevate cortisol and prolactin levels (less than GHRP-6)
Contraindications
  • Active malignancy or history of cancer (GH promotes cell proliferation)
  • Pregnancy and breastfeeding
  • Pituitary tumors or prior pituitary surgery
  • Diabetes or pre-diabetes (risk of insulin resistance from sustained GH elevation)
  • Active malignancy (GH/IGF-1 elevation contraindicated)
  • Pregnancy and breastfeeding
  • Pituitary disorders (outside diagnostic context)
  • Diabetes and cardiovascular conditions (GH affects glucose metabolism)
Regulatory (US)Not FDA-approved. Research chemical only. WADA-banned under Section S2 (growth factors and related substances).Not FDA-approved. Research chemical only. Banned by WADA.

Research Material Specifications

Catalog specifications for the corresponding research materials, including batch documentation coverage.

SpecificationCJC-1295GHRP-2
Purity Standard≥98%≥98%
CAS NumberN/A158861-67-7
Molecular FormulaBlendN/A
Available Formats10mg, 5mg, 10mg10mg
Batch COAs Published3 on file
Stock StatusIn stockOut of stock

Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.

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