Peptides for Anti-Aging Research
Overview
2 research peptides are currently studied for anti-aging research. This guide ranks them by evidence strength and covers their mechanisms, safety profiles, and current clinical status.
Pinealon — Preclinical / Uncontrolled Russian Studies
Evidence Rating: D Category: Nootropic / Neuroprotective
Pinealon (Glu-Asp-Arg, EDR) is a synthetic tripeptide (MW ~418 g/mol) developed by Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology as a bioregulatory peptide targeting brain and pineal gland function. It is part of the Khavinson peptide bioregulator family. Eviden...
Key claims: Neuroprotective effects in cell culture; Enhances melatonin production.
Cortagen — Preclinical / Uncontrolled Russian Studies
Evidence Rating: D Category: Nootropic / Neuroprotective
Cortagen (Ala-Glu-Asp-Leu, AEDL) is a synthetic tetrapeptide (MW ~446 g/mol) developed by Vladimir Khavinson as a bioregulatory peptide targeting the cerebral cortex. Like other Khavinson bioregulators, it is proposed to normalize gene expression in brain tissue. Evidence is limited to Russian precl...
Key claims: Neuroprotective effects in ischemia models; Normalization of cortical gene expression.