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Dihexa (PNB-0408): Structure, a Proposed HGF/c-Met Mechanism and a Retracted Literature

Dihexa (PNB-0408) is a synthetic, metabolically stabilised analogue of angiotensin IV. Its structure, the HGF/c-Met mechanism proposed for it, the 2025 retraction of the paper that mechanism rests on, the notice of concern on a second paper, and why almost the whole literature comes from one laboratory.