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All Comparisons

Ipamorelin vs CJC-1295

Research material comparison: purity standards, available formats, molecular data, batch COA documentation, and regulatory status. For in vitro research use only.

Ipamorelin: DCJC-1295: D
AttributeIpamorelinCJC-1295
CategoryGrowth Hormone SecretagogueGrowth Hormone Secretagogue
Evidence RatingD — PreclinicalD — Preclinical
Clinical StatusResearch-only / Not approved for human useResearch-only / Not approved for human use
MechanismIpamorelin (sequence: Aib-His-D-2Nal-D-Phe-Lys-NH2) selectively binds to the Growth Hormone Secretagogue Receptor (GHS-R1a) on anterior pituitary somatotroph cells, increasing cAMP and activating protein kinase A to promote pulsatile GH secretion. Its structural specificity means it fits only the GH...CJC-1295 binds to GHRH receptors (GHRHR) on pituitary somatotroph cells, activating intracellular cAMP signaling to stimulate both the transcription of the GH gene and pulsatile release of endogenous growth hormone, which in turn increases IGF-1 levels. The released IGF-1 travels to muscle tissue fo...
Half-Life~2 hoursNo DAC (mod GRF 1-29): ~30 min; With DAC: ~8 days
BioavailabilityHigh SC bioavailability—
Molecular Weight~711.9 g/molNo DAC: ~3367.9 g/mol; With DAC: ~3647.3 g/mol
WADA StatusProhibitedProhibited
Research Half-Life~2 hoursNo DAC (mod GRF 1-29): ~30 min; With DAC: ~8 days
Key Use Cases
  • Anti-Aging
  • Body Composition
  • Sleep
  • Anti-Aging
  • Body Composition
Safety Concerns
  • Widely regarded as the mildest GHS available; minimal side effects in published animal and human studies
  • Common: injection site reactions (redness, swelling, bruising) in 15-30% of users, resolving within 24-48 hours
  • Common: mild temporary "head rush" or flushing immediately after injection due to sudden vasodilation
  • Common: transient flushing/"head rush" within 5-10 minutes post-injection — hallmark of a potent injection, harmless and brief
  • Self-reported: flu-like symptoms, headaches, irritability, anxiety, nausea, hives (mild and transient)
  • Water retention and edema (dose-dependent; elevated GH causes sodium/water retention via kidneys)
Contraindications
  • Active malignancy or personal/family history of cancer (GH promotes cell proliferation)
  • Pregnancy and breastfeeding
  • Pituitary disorders or prior pituitary surgery
  • Diabetes with retinopathy (GH can affect blood glucose and worsen retinopathy)
  • Active malignancy or history of cancer (GH promotes cell proliferation)
  • Pregnancy and breastfeeding
  • Pituitary tumors or prior pituitary surgery
  • Diabetes or pre-diabetes (risk of insulin resistance from sustained GH elevation)
Regulatory (US)Not FDA-approved. Research chemical only. WADA-banned (S2 growth factor).Not FDA-approved. Research chemical only. WADA-banned under Section S2 (growth factors and related substances).

Research Material Specifications

Catalog specifications for the corresponding research materials, including batch documentation coverage.

SpecificationIpamorelinCJC-1295
Purity Standard≥98%≥98%
CAS Number170851-70-4N/A
Molecular FormulaC₃₈H₄₉N₉O₅Blend
Available Formats10mg, 10mg10mg, 5mg, 10mg
Batch COAs Published2 on file3 on file
Stock StatusIn stockIn stock

Availability at Volta Peptides

Ipamorelin 10mg

≥98% purity · HPLC verified · In stock

$49

CJC-1295 No DAC + Ipamorelin 10mg (5+5)

≥98% purity · HPLC verified · In stock

$49

Research Disclaimer: This comparison is provided for educational purposes only. All products are sold exclusively for in vitro research use. The information presented is based on published preclinical and clinical research and does not constitute medical advice. Consult a qualified healthcare professional before making any decisions regarding peptide use.

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