IGF-1 LR3 in Canada
Growth Factor
Also known as Long R3 IGF-1, Long Arg3 Insulin-like Growth Factor-1.
IGF-1 LR3 is not in the catalogue yet. When it ships it will be dispatched from British Columbia, so Canadian orders clear no customs and cross no border. Add your email below and you will hear the day it is available.
Notify me when IGF-1 LR3 is available
One email when it launches. Nothing else.
Get Notified When Available
This product is currently out of stock. Enter your email and we'll notify you the moment it's back.
About IGF-1 LR3
IGF-1 LR3 is a modified version of insulin-like growth factor 1 (IGF-1) with an extended N-terminal sequence (13 additional amino acids) and an arginine-to-glutamic acid substitution at position 3. These modifications dramatically reduce binding to IGF-binding proteins (IGFBPs), resulting in a half-life of 20-30 hours (vs 12-15 hours for native IGF-1) and approximately 3x greater potency. It is one of the most potent anabolic peptides available and is WADA-banned.
Mechanism
IGF-1 LR3 binds to IGF-1 receptors on target cells with high affinity, initiating tyrosine kinase signaling that activates the PI3K/Akt/mTOR pathway, increasing protein synthesis, glucose uptake, and cellular survival while inhibiting muscle protein breakdown (anti-catabolic). Its low affinity for IGFBPs means more free circulating IGF-1 LR3 is available for receptor activation compared to native IGF-1. It promotes satellite cell proliferation and differentiation in skeletal muscle (hyperplasia — new muscle cell formation, not just hypertrophy), enhances nutrient partitioning toward lean tissue, and has insulin-like effects on glucose metabolism.
In the meantime
Volta Peptides supplies materials strictly for in-vitro laboratory research. Nothing on this page is a drug, supplement, cosmetic or food, and nothing here is intended for human or animal use, clinical application or diagnostic procedures. The research summary above describes published literature and is not a claim of therapeutic benefit or a statement that this compound is offered for such use.